We offer TOC instruments for the pharmaceutical industry.

MULTI N/C PHARMA UV – TOC ANALYSIS AT ULTRA-LOW LEVELS

An efficient TOC instrument based on wet-chemical UV oxidation, ideal for TOC analysis in ultra-pure water samples and for cleaning validation, with injection volumes of up to 20.0 ml.

Features:

• TOC determination in direct NPOC mode without blank subtraction, offering optimal sensitivity and precision. TOC measurement <1 ppm without oxidation reagent.
• Lowest operating costs – no catalyst or combustion tube, and no additional reagents required.
• Extended working range up to 10,000 ppm using user-preparable oxidation reagents.

MULTI N/C PHARMA HT – FLEXIBLE TOC/TN ANALYSIS

A versatile instrument featuring a high-temperature combustion furnace for TOC/TN analysis in ultra-pure water and for cleaning validation. As an option, direct combustion of swabs enables detection of insoluble or barely soluble residues in TOC cleaning validation.

Features:

• TOC determination in direct NPOC mode for the highest precision in ultra-low concentration ranges.
• Injection volume up to 3.0 ml.
• Optional cleaning validation for TN.

MULTI N/C 3100 PHARMA – HIGH SAMPLE THROUGHPUT FOR TOC/TN ANALYSIS

This instrument uses high-temperature catalytic combustion and offers a wide dynamic range, effective cleaning functionality, a high degree of automation, and parallel sample streams for large-volume throughput.

Features:

• TOC determination in direct NPOC mode for excellent precision at ultra-low levels.
  Injection volume up to 1.0 ml.
• Covers a TOC concentration range from 0 to 30,000 ppm.
• Automatic sample acidification and efficient reverse rinsing function prevent contamination and carryover between samples with varying concentrations.

MULTI N/C 2100S PHARMA – THE SPECIALIST FOR TOTAL PROTEIN ANALYSIS

An instrument for TN analysis using high-temperature catalytic combustion and CLD detection. Suitable for efficient protein analysis in vaccine production or TN cleaning validation. Minimal testing effort is required, and the system allows a high degree of automation.

Features:

• No sample contamination or carryover due to direct injection without septa, using a microliter syringe and effective cleaning.
• Low sample volumes, with typical injection volumes between 50–200 µl (max 1.8 ml), helping to reduce costs for expensive matrices, e.g. in vaccine quality control.
• Wide working range from 0 to 200 ppm TN.
• High degree of automation for large test series (up to 112 HPLC vial positions).
  24-hour unattended operation enabled by built-in Self Check System (SCS).

If you have any questions about TOC for the pharmaceutical industry, feel free to get in touch!